Flanker Chris Robshaw and full-back Mike Brown are doubts for England’s Six Nations opener against Italy.
Robshaw, 31, has a back injury, while his Harlequins team-mate Brown, 32, is hampered by blurred vision, taking England’s injury list to 16 players.
England have won all 23 meetings with Italy and will be strong favourites to maintain their 100% record when they launch their bid for a third Six Nations title in a row.
The six nation tournament kicks off next weekend as Wales takes on Scotland and France to face Ireland.
England’s injury list:
Forwards: Tom Curry, Charlie Ewels, Ellis Genge, Nathan Hughes, Matt Mullan, Beno Obano, Kyle Sinckler, Will Spencer, Billy Vunipola.
Backs: Elliot Daly, Piers Francis, Semesa Rokoduguni, Henry Slade. (Ben Te’o is returning to fitness with England but has not played since October)
