Child jabs halted in trial as adult clot link probed
April 7, 2021 5:45 am
A trial of the Oxford-AstraZeneca Covid vaccine on children has stopped giving out jabs while the UK’s medicines regulator investigates a possible link with rare blood clots in adults.
Prof Andrew Pollard from the University of Oxford told the BBC there were no safety concerns with the trial itself, but its scientists were waiting for further information.
Around 300 volunteers signed up.
Earlier, PM Boris Johnson said people should get their jab when invited.
More than 31.6 million people in the UK have had a first vaccine dose.
A total of 5.4 million people have received a second dose.
Two vaccines – developed by Oxford-AstraZeneca and Pfizer-BioNtech – are being used in the UK, while a third – from Moderna – has been approved.
The trial of the Oxford-AstraZeneca vaccine on children, which started in February, is assessing whether the jab produces a strong immune response in those aged between six and 17.
Its suspension comes after a European Medicines Agency (EMA) official, speaking in a personal capacity, said there appeared to be a link with the jab and rare blood clots.
Confirming that the trial on children was being paused, Prof Pollard said: “Whilst there are no safety concerns in the paediatric clinical trial, we await additional information from the MHRA on its review of rare cases of thrombosis/thrombocytopaenia that have been reported in adults, before giving any further vaccinations in the trial.”
Participants are advised to continue to attend all scheduled visits and can contact the trial sites if they have any questions.
Updates from the EMA and the UK’s regulator, the Medicines and Healthcare Products Regulatory Agency (MHRA), are expected in the coming days.
The EMA said its safety committee had “not yet reached a conclusion and the review is currently ongoing”.
The MHRA says the benefits of the jab continue to outweigh any risk.