England and Saracens number eight Billy Vunipola has been ruled out for 12 weeks after suffering a broken arm against Glasgow on Sunday.

Vunipola will be joined on the sidelines by brother Mako and Nick Isiekwe after all three were forced off in Saracens’ 13-3 Champions Cup win.

The injury news is not only a setback to Saracens but also England as they prepare for their upcoming November international showdowns against South Africa, New Zealand, Japan and Australia.